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1

Novel approach to studying N-methyl-D-aspartate receptor function in the kindling model of epilepsy

James O. McNamara, Douglas W. Bonhaus, J. Victor Nadler

Journal:

Drug Development Research

Année:

1989

Langue:

english

Fichier:

PDF, 649 KB

english, 1989

2

Method of lesioning brainstem determines seizure probability

Jon M. Silver, Douglas W. Bonhaus, James O. McNamara

Journal:

Journal of Neuroscience Methods

Année:

1986

Langue:

english

Fichier:

PDF, 478 KB

english, 1986

3

Some benzenesulfonamido-substituted valerophenones that are selective antagonists for the 5-HT2C receptor

Klaus K. Weinhardt, Douglas W. Bonhaus, Andrea De Souza

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

1996

Langue:

english

Fichier:

PDF, 223 KB

english, 1996

4

Cloning and Expression of a 5-Hydroxytryptamine7 Receptor Positively Coupled to Adenylyl Cyclase

Ann-ping Tsou, Alan Kosaka, Chinh Bach, Patti Zuppan, Calvin Yee, Leonard Tom, Robert Alvarez, Scott Ramsey, Douglas W. Bonhaus, Eric Stefanich, Lyn Jakeman, Richard M. Eglen, Hardy W. Chan

Journal:

Journal of Neurochemistry

Année:

1994

Langue:

english

Fichier:

PDF, 1.68 MB

english, 1994

5

Allosteric Interactions Among Agonists and Antagonists at 5-Hydroxytryptamine3 Receptors

Douglas W. Bonhaus, Eric Stefanich, Dana N. Loury, Sherry A. O. Hsu, Richard M. Eglen, Erik H. F. Wong

Journal:

Journal of Neurochemistry

Année:

1995

Langue:

english

Fichier:

PDF, 671 KB

english, 1995

6

Differential regulation of muscarinic M1receptors by orthosteric and allosteric ligands

Christopher N Davis, Stefania Risso Bradley, Hans H Schiffer, Mikael Friberg, Kristian Koch, Bo-Ragnar Tolf, Douglas W Bonhaus, Jelveh Lameh

Journal:

BMC Pharmacology

Année:

2009

Langue:

english

Fichier:

PDF, 2.37 MB

english, 2009

7

Discovery of potential antipsychotic agents possessing pro-cognitive properties

Jelveh Lameh, Krista McFarland, Jorgen Ohlsson, Fredrik Ek, Fabrice Piu, Ethan S. Burstein, Ali Tabatabaei, Roger Olsson, Stefania Risso Bradley, Douglas W. Bonhaus

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Année:

2012

Langue:

english

Fichier:

PDF, 352 KB

english, 2012

8

Effects of cannabinoid receptor ligands on psychosis-relevant behavior models in the rat

Renee S. Martin, Robert L. Secchi, Eric Sung, Martine Lemaire, Douglas W. Bonhaus, Linda R. Hedley, David A. Lowe

Journal:

Psychopharmacology

Année:

2003

Langue:

english

Fichier:

PDF, 475 KB

english, 2003

9

Enhanced delayed matching performance in younger and older macaques administered the 5-HT4 receptor agonist, RS 17017

A. V. Terry Jr., Jerry J. Buccafusco, William J. Jackson, Mark A. Prendergast, David J. Fontana, Erik H. F. Wong, Douglas W. Bonhaus, Paul Weller, Richard M. Eglen

Journal:

Psychopharmacology

Année:

1998

Langue:

english

Fichier:

PDF, 287 KB

english, 1998

10

TCP binding: A tool for studying NMDA receptor-mediated neurotransmission in kindling

Douglas W. Bonhaus, James O. McNamara

Journal:

Neuroscience & Biobehavioral Reviews

Année:

1989

Langue:

english

Fichier:

PDF, 662 KB

english, 1989

11

Labelling of 5-Hydroxytryptamine3 Receptors with a Novel 5-HT3 Receptor Ligand, [3H]RS-42358–197

Erik H. F. Wong, Douglas W. Bonhaus, Irene Wu, Eric Stefanich, Richard M. Eglen

Journal:

Journal of Neurochemistry

Année:

1993

Langue:

english

Fichier:

PDF, 922 KB

english, 1993

12

Catecholamine modulatory effects of nepicastat (RS-25560-197), a novel, potent and selective inhibitor of dopamine-β-hydroxylase

William C. Stanley, Bin Li, Douglas W. Bonhaus, Lowell G. Johnson, Keiho Lee, Seth Porter, Keith Walker, Greg Martinez, Richard M. Eglen, Roger L. Whiting, Sharath S. Hegde

Journal:

British Journal of Pharmacology

Année:

1997

Langue:

english

Fichier:

PDF, 365 KB

english, 1997

13

RS-127445: a selective, high affinity, orally bioavailable 5-HT2B receptor antagonist

Douglas W Bonhaus, Lee A Flippin, Robert J Greenhouse, Saul Jaime, Cindy Rocha, Mark Dawson, Kristine Van Natta, L K Chang, Tess Pulido-Rios, Andrea Webber, Edward Leung, Richard M Eglen, Graeme R Mar

Journal:

British Journal of Pharmacology

Année:

1999

Langue:

english

Fichier:

PDF, 207 KB

english, 1999

14

Pharmacological Characterization of 5-Hydroxytryptamine3Receptors in Murine Brain and Ileum Using the Novel Radioligand [3H]RS-42358–197: Evidence for Receptor Heterogeneity

Douglas W. Bonhaus, Erik H. F. Wong, Eric Stefanich, Elizabeth A. Kunysz, Richard M. Eglen

Journal:

Journal of Neurochemistry

Année:

1993

Langue:

english

Fichier:

PDF, 568 KB

english, 1993

15

AC260584 (4-[3-(4-butylpiperidin-1-yl)-propyl]-7-fluoro-4H-benzo[1,4]oxazin-3-one), a selective muscarinic M1 receptor agonist, increases acetylcholine and dopamine release in rat medial prefrontal cortex and hippocampus

Zhu Li, Douglas W. Bonhaus, Mei Huang, Adam J. Prus, Jin Dai, Herbert Y. Meltzer

Journal:

European Journal of Pharmacology

Année:

2007

Langue:

english

Fichier:

PDF, 441 KB

english, 2007

16

Pharmacology of N-desmethylclozapine

Jelveh Lameh, Ethan S. Burstein, Eve Taylor, David M. Weiner, Kimberly E. Vanover, Douglas W. Bonhaus

Journal:

Pharmacology & Therapeutics

Année:

2007

Langue:

english

Fichier:

PDF, 217 KB

english, 2007

17

Ligand Efficacy and Potency at Recombinant α2 Adrenergic Receptors: Agonist-Mediated [35s]gtpγs Binding

Jeffrey R Jasper, John D Lesnick, L.Katy Chang, Susan S Yamanishi, Thomas K Chang, Sherry A.O Hsu, David A Daunt, Douglas W Bonhaus, Richard M Eglen

Journal:

Biochemical Pharmacology

Année:

1998

Langue:

english

Fichier:

PDF, 539 KB

english, 1998

18

The pharmacology and distribution of human 5-hydroxytryptamine2B (5-HT2b) receptor gene products: comparison with 5-HT2a and 5-HT2c receptors

Douglas W. Bonhaus, Chinh Bach, Andrea DeSouza, F.H. Rick Salazar, Barbara D. Matsuoka, Patricia Zuppan, Hardy W. Chan, Richard M. Eglen

Journal:

British Journal of Pharmacology

Année:

1995

Langue:

english

Fichier:

PDF, 1.47 MB

english, 1995

19

2-(Quinuclidin-3-yl)pyrido[4,3-b]indol-1-ones and isoquinolin-1-ones. Potent conformationally restricted 5-HT3 receptor antagonists

Clark, Robin D., Miller, Aaron B., Berger, Jacob, Repke, David B., Weinhardt, Klaus K., Kowalczyk, Bruce A., Eglen, Richard M., Bonhaus, Douglas W., Lee, Chi Ho

Journal:

Journal of Medicinal Chemistry

Année:

1993

Langue:

english

Fichier:

PDF, 3.54 MB

english, 1993

20

The role of substantia nigra in the development of kindling: pharmacologic and lesion studies

Cheolsu Shin, Jon M. Silver, Douglas W. Bonhaus, James O. McNamara

Journal:

Année:

1987

Langue:

english

Fichier:

PDF, 569 KB

english, 1987

21

Activity of locus coeruleus neurons in amygdala kindled rats: role in the suppression of afterdischarge

Douglas W. Bonhaus, James O. McNamara

Journal:

Année:

1987

Langue:

english

Fichier:

PDF, 1.11 MB

english, 1987

22

Anticonvulsant action of intranigral γ-vinyl-GABA: role of noradrenergic neurotransmission

Douglas W. Bonhaus, James O. McNamara

Journal:

Année:

1988

Langue:

english

Fichier:

PDF, 466 KB

english, 1988

23

A radiohistochemical measure of [3H]TCP binding to the activated NMDA-receptor-gated ion channel in rat brain

David A. Hosford, Douglas W. Bonhaus, James O. McNamara

Journal:

Année:

1990

Langue:

english

Fichier:

PDF, 1.03 MB

english, 1990

24

Decreased density, but not number, N-methyl-D-aspartate, glycine and phencyclidine binding sites in hippocampus of senescent rats

Douglas W. Bonhaus, W. Bryan Perry, James O. McNamara

Journal:

Année:

1990

Langue:

english

Fichier:

PDF, 391 KB

english, 1990

25

Activation of substantia nigra pars reticulata neurons: role in the initiation and behavioral expression of kindled seizures

Douglas W. Bonhaus, Richard D. Russell, James O. McNamara

Journal:

Année:

1991

Langue:

english

Fichier:

PDF, 872 KB

english, 1991

26

Biochemical evidence that glycine allosterically regulates an NMDA receptor-coupled ion channel

Douglas W. Bonhaus, B. Carlton Burge, James O. McNamara

Journal:

European Journal of Pharmacology

Année:

1987

Langue:

english

Fichier:

PDF, 144 KB

english, 1987

27

Radiohistochemical demonstration of NMDA/glycine-channel activation in rat hippocampus

David A. Hosford, Douglas W. Bonhaus, James O. McNamara

Journal:

European Journal of Pharmacology

Année:

1988

Langue:

english

Fichier:

PDF, 524 KB

english, 1988

28

Different densities of 5-HT3 receptors are labeled by [3H]quipazine, [3H]GR 65630 and [3H]geanisetron

Erik H.F. Wong, Douglas W. Bonhaus, Jeffrey A. Lee, Irene Wu, Dana N. Loury, Richard M. Eglen

Journal:

Neuropharmacology

Année:

1993

Langue:

english

Fichier:

PDF, 618 KB

english, 1993

29

The β1 Sodium Channel Subunit Modifies the Interactions of Neurotoxins and Local Anesthetics with the Rat Brain IIA α Sodium Channel in Isolated Membranes but not in Intact Cells

DOUGLAS W BONHAUS, RONALD C HERMAN, CHRISTINE M BROWN, ZHEN CAO, LI-FENG CHANG, DANA N LOURY, PING SZE, LI ZHANG, JOHN C HUNTER

Journal:

Neuropharmacology

Année:

1996

Langue:

english

Fichier:

PDF, 1.82 MB

english, 1996

30

Allosteric modulation of [3H]gabapentin binding by ruthenium red

Michele T Taylor, Douglas W Bonhaus

Journal:

Neuropharmacology

Année:

2000

Langue:

english

Fichier:

PDF, 133 KB

english, 2000

31

Intranigral dynorphin-1-13 suppresses kindled seizures by a naloxone-insensitive mechanism

Douglas W. Bonhaus, Lewis C. Rigsbee, James O. McNamara

Journal:

Année:

1987

Langue:

english

Fichier:

PDF, 456 KB

english, 1987

32

P1-013: Antipsychotic-like activity of pimavanserin, A 5-ht2a inverse agonist, in putative animal models of Alzheimer's disease psychosis

Krista McFarland, Sean A. Gorman, Douglas W. Bonhaus

Journal:

Alzheimer's & Dementia

Année:

2008

Langue:

english

Fichier:

PDF, 55 KB

english, 2008

33

Neuroprotective effects of a novel Aß-protein stabilizer in APP transgenic mouse model of Alzheimer's disease

Diana Price, Wolfgang Wrasidlo, Igor Tsigelny, Douglas Bonhaus, Amy Paulino, Michael Mante, Chandra Inglis, Anthony Adame, Herbert Moessler, Edward Rockenstein, Eliezer Masliah

Journal:

Alzheimer's & Dementia

Année:

2012

Langue:

english

Fichier:

PDF, 141 KB

english, 2012

34

A method for identifying Ca ionophores using a unicellular organism

Vicki G. Stycles, Douglas W. Bonhaus, Jerry B. Hook

Journal:

Journal of Pharmacological Methods

Année:

1980

Langue:

english

Fichier:

PDF, 793 KB

english, 1980

35

Actions of guanidinoethane sulfonate on taurine concentration, retinal morphology and seizure threshold in the neonatal rat

Bonhaus, Douglas W., Pasantes-Morales, Hermina, Huxtable, Ryan J.

Journal:

Neurochemistry International

Année:

1985

Langue:

english

Fichier:

PDF, 967 KB

english, 1985

36

Correlations between amino acid concentrations in brains of seizure-susceptible and seizure-resistant rats

Huxtable, Ryan J., Laird, Hugh, Bonhaus, Douglas, Cole Thies, A.

Journal:

Neurochemistry International

Année:

1982

Langue:

english

Fichier:

PDF, 362 KB

english, 1982

37

Alzheimer's disease psychosis: Potential therapeutic benefit of pimavanserin, a 5-HT2A inverse agonist

McFarland, Krista, Price, Diana L., Gorman, Sean A., Johnson, Robert W., Bonhaus, Douglas W.

Journal:

Alzheimer's & Dementia

Année:

2010

Langue:

english

Fichier:

PDF, 45 KB

english, 2010

38

The effects of aluminum on microtubular integrity using in vitro and in vivo models

Bonhaus, Douglas W., McCormack, Kevin M., Mayor, Gilbert H., Mattson, Joan C., Hook, Jerry B.

Journal:

Toxicology Letters

Année:

1980

Langue:

english

Fichier:

PDF, 1.16 MB

english, 1980

39

N-methyl-D-aspartate Receptor Plasticity in Kindling: Quantitative and Qualitative Alterations in the N-methyl-D-aspartate Receptor-Channel Complex

Geng-Chang Yeh, Douglas W. Bonhaus, J. Victor Nadler and James O. McNamara

Journal:

Proceedings of the National Academy of Sciences

Année:

1989

Langue:

english

Fichier:

PDF, 827 KB

english, 1989

40

AC-186, a Selective Nonsteroidal Estrogen Receptor β Agonist, Shows Gender Specific Neuroprotection in a Parkinson’s Disease Rat Model

McFarland, Krista, Price, Diana L., Davis, Christopher N., Ma, Jian-Nong, Bonhaus, Douglas W., Burstein, Ethan S., Olsson, Roger

Journal:

ACS Chemical Neuroscience

Année:

2013

Langue:

english

Fichier:

PDF, 2.03 MB

english, 2013

41

Pimavanserin, a 5-HT2A receptor inverse agonist, reverses psychosis-like behaviors in a rodent model of Alzheimer’s disease

Price, Diana L., Bonhaus, Douglas W., McFarland, Krista

Journal:

Behavioural Pharmacology

Année:

2012

Langue:

english

Fichier:

PDF, 527 KB

english, 2012

42

Pimavanserin, a 5-HT2A inverse agonist, reverses psychosis-like behaviors in a rodent model of Parkinsonʼs disease

McFarland, Krista, Price, Diana L., Bonhaus, Douglas W.

Journal:

Behavioural Pharmacology

Année:

2011

Langue:

english

Fichier:

PDF, 491 KB

english, 2011

43

A de novo compound targeting α-synuclein improves deficits in models of Parkinson’s disease

Wrasidlo, Wolfgang, Tsigelny, Igor F., Price, Diana L., Dutta, Garima, Rockenstein, Edward, Schwarz, Thomas C., Ledolter, Karin, Bonhaus, Douglas, Paulino, Amy, Eleuteri, Simona, Skjevik, Åge A., Kouz

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 3.27 MB

english, 2016

44

Longitudinal live imaging of retinal α-synuclein::GFP deposits in a transgenic mouse model of Parkinson’s Disease/Dementia with Lewy Bodies

Price, Diana L., Rockenstein, Edward, Mante, Michael, Adame, Anthony, Overk, Cassia, Spencer, Brian, Duong-Polk, Karen X., Bonhaus, Douglas, Lindsey, James, Masliah, Eliezer

Journal:

Scientific Reports

Année:

2016

Langue:

english

Fichier:

PDF, 1.81 MB

english, 2016

45

The small molecule alpha-synuclein misfolding inhibitor, NPT200-11, produces multiple benefits in an animal model of Parkinson’s disease

Price, Diana L., Koike, Maya A., Khan, Asma, Wrasidlo, Wolfgang, Rockenstein, Edward, Masliah, Eliezer, Bonhaus, Douglas

Journal:

Scientific Reports

Année:

2018

Langue:

english

Fichier:

PDF, 2.37 MB

english, 2018

46

The 5-HT 3 Subtype of Serotonin Receptor Contributes to Nociceptive Processing via a Novel Subset of Myelinated and Unmyelinated Nociceptors

Zeitz, Karla P., Guy, Nicolas, Malmberg, Annika B., Dirajlal, Sahera, Martin, William J., Sun, Linda, Bonhaus, Douglas W., Stucky, Cheryl L., Julius, David, Basbaum, Allan I.

Journal:

Journal of Neuroscience

Année:

2002

Langue:

english

Fichier:

PDF, 481 KB

english, 2002